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Pathology

Chair

  • Nitin J. Karandikar

Director, clinical functions

  • Roseanne Meyer

Faculty

Professors

  • Gary L. Baumbach, Leslie A. Bruch, Daniel Diekema (Pathology/Internal Medicine), Frederick Domann (Pathology/Radiation Oncology/Surgery), John Harty (Pathology/Microbiology), Siegfried Janz, Chris Jensen, Nitin J. Karandikar, John D. Kemp, Patricia Kirby (Ophthalmology and Visual Sciences/Pathology), Charles F. Lynch (Epidemiology/Pathology), Steven Moore, Marcus Nashelsky, Robert A. Robinson (Pathology/Oral Pathology, Radiology, and Medicine), Nancy Rosenthal, Mary Stone (Dermatology/Pathology), Stefan Strack (Pathology/Pharmacology), Lubomir P. Turek, Steven Vincent (Oral Pathology, Radiology, and Medicine/Pathology), Thomas Waldschmidt

Associate professors

  • Vladimir Badovinac, Andrew Bellizzi, Aaron Bossler, Laila Dahmoush (Urology/Pathology), Adam Dupay (Anatomy and Cell Biology/Pathology), Hasem Habelhah, Thomas H. Haugen, Michael Henry (Molecular Physiology and Biophysics/Pathology), Carol Holman, Michael Icardi, Marina Ivanovic, Michael Knudson, Matthew Krasowski, Kevin Legge (Microbiology/Pathology), Vincent Liu (Pathology/Dermatology), David Meyerholz, Dawn Quelle (Pathology/Pharmacology), Annette Schlueter, Brian Swick (Pathology/Dermatology), Nasreen Syed (Ophthalmology and Visual Sciences/Pathology), Sergei Syrbu, Robert D. Tucker (Biomedical Engineering/Pathology), Steve Varga (Pathology/Microbiology)

Assistant professors

  • Amani Bashir, John Blau, Dennis Firchau, Bradley Ford, Katherine Gibson-Corley, Apollina Goel (Pathology/Radiation Oncology), Leana Guerin, Danniele Holanda, Stacey Klutts, Deqin Ma, Megan Samuelson, Andrean Simons-Burnett (Radiation Oncology/Pathology), Sushmita Sinha, Anthony Snow, Munir Tanas, Weizhou Zhang (Radiation Oncology/Pathology), Chen Zhao

Adjunct associate professors

  • Julia C. Goodin, Karen Honeycutt

Adjunct assistant professors

  • Michelle Catellier, Timothy Drevankyo, Yasuko Erickson, Dennis Klein, Jonathan Thompson, Jamie Weydert

Professors emeriti

  • Jo Ann Benda, Michael Cohen, Robert T. Cook, Fred Dee, Gary Doern, James A. Goeken, George F. Johnson, Thomas Kent, Frank Mitros, Michael Pfaller, Charles E. Platz, Ronald G. Strauss

Associate professors emeriti

  • Morris O. Dailey, Ronald Feld, Theodore Koerner
Graduate degree: M.S. in pathology
Web site: http://www.medicine.uiowa.edu/pathology/

The Department of Pathology offers education and training for a broad range of students, from undergraduates through postgraduate fellows and researchers. It provides basic pathology courses to health sciences students; a clinical training program for clinical laboratory scientists; a Master of Science program in pathology; residency training programs leading to American Board of Pathology certification in anatomic pathology, clinical pathology, and neuropathology; fellowship training in pathology subspecialties; and postdoctoral research training in cellular and molecular pathology.

Undergraduate Education

Pathology courses are a major component of the University's Medical Laboratory Science Program, a Bachelor of Science program that trains medical laboratory scientists; see Medical Laboratory Science in the Catalog.

M.D. Student Training

The department provides seven 12-month fellowships for M.D. students: the Emory Warner Fellowship, a full-time research position in a facet of experimental pathology; and six pathology externships, for students interested in careers as pathologists. It also offers clerkships for M.D. students in all areas of anatomical and clinical pathology.

Residency Program

The department offers 20 residency positions in pathology, which provide up to four years of training. Patients at University of Iowa Hospitals and Clinics and the Iowa City Veterans Affairs Medical Center are integral to the residency programs.

Residents gain experience in systematic rotation through the varied laboratory services, including surgical pathology, autopsy pathology, neuropathology, dermatopathology, cytology, clinical chemistry, clinical microbiology, hematology, immunopathology, molecular pathology, and transfusion medicine. They also have the opportunity to pursue one or two years of additional fellowship training in many pathology subspecialties. To learn more, see Education on the Department of Pathology web site.

Graduate Program of Study

  • Master of Science in pathology

Master of Science

The Master of Science program in pathology requires a minimum of 30 s.h. of graduate credit, including 21 s.h. of classroom work and 9 s.h. earned for research. The program trains graduate students in cell and molecular biology. Graduates work as research scientists in a range of academic and commercial laboratories, including those in the rapidly expanding biotechnology sector. Others advance to doctoral-level study.

M.S. students take a core curriculum in cell and molecular biology as well as electives suited to their individual interests. They acquire contemporary research skills by pursuing a laboratory thesis project under the guidance of a faculty member. Currently, there are active research programs in immunology, microbiology, neuroscience, signaling and apoptosis, inflammation and vascular biology, tumor biology and cancer, and virology.

Most M.S. students complete their course of study in three years.

The department encourages applicants who have earned a Bachelor of Science with a major in biology, chemistry, biochemistry, clinical laboratory science, microbiology, or zoology. Applicants must meet the admission requirements of the Graduate College; see the Manual of Rules and Regulations of the Graduate College or the Graduate College section of the Catalog. They should have an undergraduate g.p.a. of at least 3.00 and a combined verbal and quantitative score of at least 1100 on the Graduate Record Exam (GRE) General test.

For more information about graduate study, see Education on the Department of Pathology web site.

Postgraduate Training

The Department of Pathology offers postgraduate clinical fellowship programs in hematopathology, transfusion medicine, clinical microbiology, cytopathology, dermatopathology, molecular genetics pathology, and surgical pathology for physicians who have completed residency training in pathology. These fellowships consist of one to two years of diagnostic work and research.

The department provides postdoctoral research training in immunology, neuropathology, apoptosis, cancer biology, and clinical microbiology as well as in other areas of cellular and molecular pathology. These positions are open to individuals who have earned a Ph.D. or an M.D.

Facilities

The Department of Pathology is well-equipped to carry out the sophisticated technology of modern cellular and molecular pathology. It administers more than 90,000 square feet of clinical laboratories at University of Iowa Hospitals and Clinics and has individual research and core facility laboratories, including histopathology and laser capture microscopy for cellular and molecular pathology research, in the Medical Research Center, Medical Laboratories, and at the Iowa City Veterans Affairs Medical Center. Also available are Carver College of Medicine research facilities for nucleic acid chemistry, hybridoma production, flow cytometry, ultrastructural studies, protein structure, image analysis, electron spin resonance, mass spectroscopy, nuclear magnetic resonance, and laboratory animal care.

Courses

PATH:4150 (069:150) Advanced Laboratory Practice0,2,6 s.h.
Advanced laboratory practical skills. Requirements: acceptance to Clinical Laboratory Science Program.
 
PATH:4151 (069:151) MLS Program Registration0 s.h.
Requirements: admission to Medical Laboratory Science Program.
 
PATH:4152 (069:152) MLS Theory, Application, and Correlation0,3,5 s.h.
Theory, application, and correlation of medical laboratory science. Prerequisites: PATH:4150 (069:150).
 
PATH:4154 (069:154) Clinical Chemistry I0,3 s.h.
Theory, practical application, technical performance, and evaluation of clinical chemistry laboratory procedures; correlation of laboratory data with diagnosis of disease. Prerequisites: PATH:4150 (069:150).
 
PATH:4155 (069:155) Clinical Chemistry II0,3 s.h.
Advanced theory, practical application, technical performance, and evaluation of clinical chemistry laboratory procedures; correlation of laboratory data with diagnosis of disease. Prerequisites: PATH:4154 (069:154).
 
PATH:4156 (069:156) Clinical Hematology I0,4 s.h.
Introduction to theory, practical application, technical performance, and evaluation of hematological and hemostasis procedures; correlation of laboratory data with disease diagnosis. Prerequisites: PATH:4150 (069:150).
 
PATH:4157 (069:157) Clinical Hematology II0,3 s.h.
Advanced theory, practical application, technical performance, and evaluation of hematological and hemostasis procedures; correlation of laboratory data with disease diagnosis. Prerequisites: PATH:4156 (069:156).
 
PATH:4158 (069:158) Clinical Microbiology I0,4 s.h.
Introduction to theory, practical application, technical performance, and evaluation of procedures for isolation, identification, and susceptibility testing of infectious disease organisms in humans. Prerequisites: PATH:4150 (069:150).
 
PATH:4159 (069:159) Clinical Microbiology II0,4 s.h.
Advanced theory, practical application, technical performance, and evaluation of procedures for isolation, identification, and susceptibility testing of infectious disease organisms in humans. Prerequisites: PATH:4158 (069:158).
 
PATH:4160 (069:160) Clinical Immunology0-1 s.h.
Theory, application, and evaluation of immunological components, principles, and methodologies used to assess immune dysfunction; theory and application of molecular diagnostic tools. Prerequisites: PATH:4150 (069:150).
 
PATH:4162 (069:162) Clinical Immunohematology I0,3 s.h.
Introduction to theory, practical application, technical performance, and evaluation of blood bank procedures required for storage and transfusion of blood and blood components. Prerequisites: PATH:4150 (069:150).
 
PATH:4163 (069:163) Clinical Immunohematology II0,3 s.h.
Clinical immunohematology for laboratory science. Prerequisites: PATH:4162 (069:162).
 
PATH:4164 (069:164) Phlebotomy for Clinical Laboratory Science0-1 s.h.
Theory, practical application, technical performance, and evaluation of procedures used in collecting, handling, and processing blood specimens. Prerequisites: PATH:4150 (069:150).
 
PATH:4166 (069:166) Urine and Body Fluid Analysis0,2 s.h.
Theory, practical application, technical performance, and evaluation of procedures used in analyzing urine and other body fluids, including cerebrospinal, synovial, serous, and amniotic fluids. Prerequisites: PATH:4150 (069:150).
 
PATH:4170 (069:170) Clinical Laboratory Management I0,2 s.h.
Theory, practical application, technical performance, and evaluation of laboratory management principles and associated models; critical thinking, problem solving, leadership skills. Prerequisites: PATH:4150 (069:150).
 
PATH:4171 (069:171) Clinical Laboratory Management II0,2,3 s.h.
Advanced theory, application, technical performance, and evaluation of laboratory management principles and associated models; critical thinking, problem solving, leadership skills. Prerequisites: PATH:4170 (069:170).
 
PATH:4172 (069:172) Molecular Biology Methods0-1 s.h.
Introduction to theory, practical application, and evaluation of molecular biology methods.
 
PATH:5133 (069:153) Introduction to Human Pathology for Graduate Students4 s.h.
Human disease; basic disease processes, organ‑related and multisystem diseases; case analysis. Offered fall semesters. Same as PATH:8133 (069:133).
 
PATH:5260 (069:260) Translational Histopathology3 s.h.
Didactic sessions on human comparative histology, molecular and cellular pathology, and animal model applications; laboratory sessions on microscopy, histology, histotechnology, and immunohistochemistry, with group discussions of model papers; experience in scientific writing and oral presentation skills; for students who plan to investigate experimental models of human disease. Prerequisites: BISC:5201 (156:201) and BISC:5203 (156:203).
 
PATH:5270 (069:270) Pathogenesis of Major Human Diseases3 s.h.
Critical analysis of pathogenesis models in a series of major human diseases; clinical presentation, analysis of cellular and molecular events leading to the disease, discussion of key papers. Prerequisites: BISC:5201 (156:201) and BISC:5203 (156:203).
 
PATH:6220 (069:220) Seminar in Pathology1 s.h.
Current research and literature. Requirements: pathology graduate standing.
 
PATH:6720 (069:272) Translational Research in Cancer2 s.h.
Basic tumor biology and lab‑based methods applied to development of translational approaches to prevention, early diagnosis, and treatment of human cancers. Offered fall semesters of even years. Same as EPID:6720 (173:272).
 
PATH:7001 (069:288) Molecular and Cellular Biology of Cancer3 s.h.
Fundamental aspects of oncology at the cellular and molecular levels; mechanisms of cancer initiation and progression, oncogene action, DNA damage and repair, carcinogenesis by radiation, chemicals, viruses; tumor immunology, anticancer therapies. Offered spring semesters of odd years. Requirements: strong basic science background. Same as FRRB:7001 (077:288).
 
PATH:7207 (069:130) Clinical Laboratory Medicine for Physician Assistants0-1 s.h.
Theory and practice of selected clinical laboratory techniques and procedures; emphasis on effective use of clinical laboratory in diagnosis and management of disease. Requirements: Physician Assistant Studies and Services enrollment.
 
PATH:7211 (069:211) Research in Pathologyarr.
Basic aspects of pathology or clinical patient material; emphasis on experimental design, methods, literature review, obtaining formal answers to specific questions. Requirements: M.D. enrollment or graduate standing.
 
PATH:8007 (069:290) Medical Student Fellowships in Pathology (Externships)0 s.h.
First‑hand experience in autopsy, surgical and clinical pathology, teaching, and research to further understanding of disease mechanisms, normal and pathologic anatomy, laboratory use.
 
PATH:8008 (069:291) Warner Fellowship in Experimental Pathology0 s.h.
One‑year, full‑time membership in established research laboratory in the Department of Pathology or collaborating laboratory. Requirements: M.D. enrollment.
 
PATH:8133 (069:133) Introduction to Human Pathology for Graduate Students4 s.h.
Human disease; basic disease processes, organ‑related and multisystem diseases; case analysis. Offered fall semesters. Same as PATH:5133 (069:153).
 
PATH:8204 (069:205) Medical Pathology I5 s.h.
Mechanisms of disease, etiology, pathogenesis, epidemiology, major clinical manifestations of disease in organ systems. Requirements: M.D. enrollment or graduate standing.
 
PATH:8214 (069:206) Medical Pathology II5 s.h.
Mechanisms of disease, etiology, pathogenesis, epidemiology, major clinical manifestations of disease in organ systems. Requirements: PATH:8204 (069:205) and M.D. enrollment, or graduate standing.
 
PATH:8301 (069:240) Laboratory Medicine in Clinical Practicearr.
Issues in appropriate use of clinical laboratory and pathology resources in the primary care setting; case‑based approach. Requirements: third‑ or fourth‑year M.D. enrollment.
 
PATH:8401 (069:241) Autopsy Pathology Clerkshiparr.
 
PATH:8402 (069:245) Hematopathology Clerkshiparr.
 
PATH:8403 (069:246) Surgical Pathology Clerkshiparr.
 
PATH:8404 (069:247) Blood Bank Clerkshiparr.
 
PATH:8498 (069:998) Pathology On Campusarr.
 
PATH:8499 (069:999) Pathology Off Campusarr.