2014-15 General Catalog
Free Radical and Radiation Biology
Web site: http://frrbp.medicine.uiowa.edu/
The Free Radical and Radiation Biology Program provides in-depth training and research experience in the physical, chemical, and biological effects of radiation. It also focuses on the metabolic production of free radicals for biology and medicine.
Free radicals are of interest to researchers and clinicians due to their role in a variety of diseases and pathological states, including degenerative diseases of aging and cancer. Manipulation of free radical reactions and redox biology hold great promise for the future development of new therapies for a variety of human diseases. The Free Radical and Radiation Biology Program stresses the importance of these areas of research to basic science, clinical medicine, and public health.Back To Top
Four courses offered by the Free Radical and Radiation Biology Program are open to University of Iowa undergraduate students: FRRB:3130 (077:120) Radiation Safety and Radiobiology, FRRB:4000 (077:107) Special Topics: Advanced Undergraduates, FRRB:4001 (077:108) Special Topics: Advanced Undergraduates, and FRRB:5000 (077:103) Radiation Biology. Students looking for an overview of the biological effects of radiation, including the role of free radicals, will find FRRB:5000 (077:103) especially appropriate. All three courses are appropriate for students who plan to enter medicine, nuclear medicine technology, environmental health, or related programs.Back To Top
Graduate Programs of Study
The Carver College of Medicine administers graduate programs in free radical and radiation biology; graduate degrees are granted through the Graduate College. See Carver College of Medicine and Graduate College in the Catalog for general information about study in medicine and graduate study at the University.Back To Top
Master of Science, Doctor of Philosophy
The Master of Science in free radical and radiation biology requires a minimum of 30 s.h. of graduate credit; the Doctor of Philosophy requires a minimum of 72 s.h. of graduate credit.
The M.S. and Ph.D. programs are open to graduate students with a background in physics, chemistry, mathematics, biology, health sciences, veterinary medicine, or engineering.
After completing the introductory course FRRB:5000 (077:103) Radiation Biology, students typically concentrate on a particular aspect of the field. Some students elect to focus on radiation and cancer biology, while others choose to emphasize free radical biology.
In addition to formal lectures and some structured laboratory exercises, plans of study for free radical and radiation biology students involve small-group conferences, discussions, and seminars. Ph.D. students are encouraged to spend at least one semester as teaching assistants, for which no registration is required and no academic credit is given.
Many of the department’s graduate students elect to take FRRB:3130 (077:120) Radiation Safety and Radiobiology, a course that covers safe operation of radiation-producing equipment and handling of radioactive materials, regulations and regulatory agencies, formulas and techniques in radiation protection programs, radiation protection, and other topics.Back To Top
Postdoctoral training is available by arrangement with the program's director and individual faculty members. Contact the Free Radical and Radiation Biology Program.Back To Top
Graduate students are supported as graduate assistants from funds available through research grants and contracts or from departmental funds. Individual postdoctoral awards also may be available; the candidate and his or her faculty sponsor apply for them jointly.Back To Top
The Free Radical and Radiation Biology Program is the home of the Radiation and Free Radical Research Core Lab (RFRRC). The lab operates a 300 kVp orthovoltage X-ray generator and other radiation sources, including a 8,000-Curie Cs-137 irradiator. Students and staff have access to additional core lab support through RFRRC, with services and expertise related to analytical chemistry (EPR services) and redoxbiology, biochemistry (AES services), and linear accelerators in the Department of Radiation Oncology.
The program has a number of radiation detectors and counters, including liquid scintillation counters. It also has ultraviolet/visible spectrophotometers; various types of equipment for densitometry, chromatography, and electrophoresis; molecular biology equipment, including thermal cyclers; an automatic cell counter and particle sizer; tissue culture facilities; Typhoon Phosphoimager; HPLC; Electron Spin Resonance Spectrometers; and nitric oxide analyzers. Visit Radiation and Free Radical Research Core on the program's web site to learn more.Back To Top
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Updated July 2014