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Translational Biomedicine

Chair

  • Gary W. Hunnninghake (Internal Medicine)

Executive committee

  • Nancy Andreasen (Psychiatry), David Eichmann (Library and Information Science/Computer Science), Sarah England (Physiology), Janet Fairley (Dermatology), Vicki Grassian (Chemistry), William Haynes (Internal Medicine), Steven Maravetz (Health Science Relations), Jeff Murray (Pediatrics/Biology/Pediatric Dentistry/Epidemiology), Michael O'Hara (Psychology), Gary Rosenthal (Internal Medicine), James Torner (Epidemiology), Donald Yarbrough (Psychological and Quantitative Foundations/Educational Policy and Leadership Studies)

Affiliated faculty

  • Francois M. Abboud (Internal Medicine/Molecular Physiology and Biophysics), Nancy Andreasen (Psychiatry), Michael A. Apicella (Microbiology), Gale A. Bishop (Microbiology/Internal Medicine), Joseph A. Buckwalter (Orthopaedics and Rehabilitation), Garry R. Buettner (Free Radical and Radiation Biology), Trudy L. Burns (Biostatistics), John J. Callaghan (Orthopaedics and Rehabilitation/Biomedical Engineering), Kevin P. Campbell (Molecular Physiology and Biophysics), Barry Carter (Pharmacy), Thomas L. Casavant (Electrical and Computer Engineering/Biomedical Engineering/Ophthalmology and Visual Sciences), Michael B. Cohen (Pathology), Elizabeth Chrischilles (Cpidemiology), Beverley L. Davidson (Internal Medicine), David Eichmann (Library and Information Science/Computer Science), Bruce Gantz (Otolaryngology--Head and Neck Surgery), Gerald F. Gebhart (Pharmacology), E. Peter Greenberg (Microbiology), Gregory S. Hageman (Ophthalmology and Visual Sciences), William Haynes (Internal Medicine), Donald D. Heistad (Internal Medicine/Pharmacology), Eric A. Hoffman (Radiology/Biomedical Engineering), Matthew A. Howard III (Neurosurgery), Gary Hunninghake (Internal Medicine), Joel Kline (Internal Medicine), Ronald M. Lauer (Pediatrics), Steven R. Lentz (Internal Medicine), Steven M. Levy (Dentistry), Charles F. Lynch (Epidemiology), Allyn L. Mark (Internal Medicine), Paul B. McCray (Pediatrics), Geoffrey McLennan (Internal Medicine), Jeff Murray (Pediatrics/Biology/Pediatric Dentistry/Epidemiology), Larry W. Oberley (Free Radical and Radiation Biology), M. Sue O'Dorisio (Pediatrics), Michael O'Hara (Psychology), Stanley Perlman (Pediatrics/Microbiology), Timothy L. Ratliff (Urology), Matthew Rizzo (Neurology/Industrial Engineering), Robert G. Robinson (Psychiatry), Gary Rosenthal (Internal Medicine), Andrew F. Russo (Molecular Physiology and Biophysics), D. Michael Shasby (Internal Medicine), Curt D. Sigmund (Internal Medicine/Molecular Physiology and Biophysics), Richard J.H. Smith (Otolaryngology--Head and Neck Surgery), Arthur A. Spector (Biochemistry/Internal Medicine), Clark M. Stanford (Dentistry), Jack T. Stapleton (Internal Medicine), John B. Stokes III (Internal Medicine), Edwin M. Stone (Ophthalmology and Visual Sciences), William T. Talman (Neurology), Marita G. Titler (Nursing), Veronica Vieland (Biostatistics/Psychiatry), Robert B. Wallace (Epidemiology/Internal Medicine), George J. Weiner (Internal Medicine), Joel V. Weinstock (Internal Medicine), Jerrold P. Weiss (Internal Medicine), Michael J. Welsh (Internal Medicine/Molecular Physiology and Biophysics), Mary E. Wilson (Internal Medicine/Microbiology), Fred Wolinsky (Health Management and Policy), Joseph Zabner (Internal Medicine)
Graduate degrees: M.S., Ph.D. in Translational Biomedicine
Web site: http://icts.uiowa.edu

The Translational Biomedicine Program prepares skilled clinicians to pursue new knowledge about health and disease through patient-based research. The program's goal is to support the medical research enterprise in its efforts to advance the prevention, treatment, and cure of disease.

Students in the program are trained to conduct rigorous, original clinical investigations using basic biological and physiological principles. They receive didactic training and engage in substantial mentored research opportunities in the areas of disease mechanisms, or etiology; new clinical insights into diagnosis or natural history of disease; objective assessment and outcome of therapeutic intervention; medical informatics; and development of new approaches to therapeutics.

Graduate Programs

The program offers a Master of Science and a Doctor of Philosophy in translational biomedicine.

Master of Science

The Master of Science in translational biomedicine requires course work and research equivalent to 54 s.h. of graduate credit. Each student's plan of study for the three-year program is based on his or her chosen discipline.

All students take background courses in epidemiology, study design, and statistics as well as advanced courses in basic sciences relevant to their individual research areas.

Students also must write a proposal for a K23 Mentored Patient-Oriented Research Career Development Award from the National Institutes of Health. For M.S. students, the K23 proposal replaces the thesis. A draft of the K23 proposal must pass an internal review by the end of the student's second year.

Students may choose to pursue research areas in any of the health sciences disciplines, and they enjoy considerable flexibility in scheduling course work and beginning research.

The following courses are required. All students must register for 050:225 Translational Biomedical Research and 173:163 Seminar in Clinical and Translational Research each semester in the program. 

173:140 Epidemiology I: Principles 3 s.h.
173:150 Introduction to Clinical Epidemiology 2-3 s.h.
173:152 Clinical Research Career Development 1 s.h.
171:161 Introduction to Biostatistics 3 s.h.
173:161 Patient-Oriented Research Data Analysis 3 s.h.
173:163 Seminar in Clinical and Translational Research 1 s.h.
173:211 Grant Writing for Clinical Investigators 1 s.h.
050:225 Translational Biomedical Research arr.
173:240 Epidemiology II: Advanced Methods 4 s.h.
173:290 Intervention and Clinical Trials 3 s.h.
173:295 Clinical Research Ethics 2 s.h.

The following is a sample schedule for the Master of Science.

First Year
Summer Session
173:140 Epidemiology I: Principles 3 s.h.
173:152 Clinical Research Career Development 1 s.h.
171:161 Introduction to Biostatistics 3 s.h.

Fall Semester 
051:121 Introduction to Bioinformatics 4 s.h.
173:150 Introduction to Clinical Epidemiology 2-3 s.h.
173:290 Intervention and Clinical Trials 3 s.h.
173:163 Seminar in Clinical and Translational Research 1 s.h.
050:225 Translational Biomedical Research arr.
Spring Semester 
173:161 Patient-Oriented Research Data Analysis 3 s.h.
173:240 Epidemiology II: Advanced Methods 4 s.h.
173:295 Clinical Research Ethics 2 s.h.
173:163 Seminar in Clinical and Translational Research 1 s.h.
050:225 Translational Biomedical Research arr.

Second Year
Summer Session
173:211 Grant Writing for Clinical Investigators 1 s.h.

Fall Semester 
Elective 3 s.h.
Elective 3 s.h.
Elective 3 s.h.
173:163 Seminar in Clinical and Translational Research 1 s.h.
050:225 Translational Biomedical Research arr.

Spring Semester 
173:163 Seminar in Clinical and Translational Research 1 s.h.
050:225 Translational Biomedical Research arr.

Third Year
Summer Session
050:225 Translational Biomedical Research arr.

Fall Semester 
173:163 Seminar in Clinical and Translational Research 1 s.h.
050:225 Translational Biomedical Research arr.
Spring Semester 
173:163 Seminar in Clinical and Translational Research 1 s.h.
050:225 Translational Biomedical Research arr.

Doctor of Philosophy

The Doctor of Philosophy in translational biomedicine requires a minimum of 72 s.h. of graduate credit. Ph.D. students build on their M.S. study plan with more advanced work. For information about the Ph.D., contact the Translational Biomedicine Program.

Admission

The Translational Biomedicine Program welcomes students with diverse educational and scientific backgrounds and varied research interests. Applicants to the program should have a strong interest and background in a health science profession and knowledge of basic sciences and medicine. They should hold an advanced degree in one of the health sciences (e.g., M.D., D.O., D.D.S., D.V.M., M.S.N., Pharm.D., Ph.D.).

Applicants must meet the admission requirements of the Graduate College; see the Manual of Rules and Regulations of the Graduate College or the Graduate College section of the Catalog.

Admission is based on applicants' undergraduate and graduate academic achievement, performance on the Graduate Record Examination (GRE) General Test, and letters of recommendation. Applicants whose first language is not English must take the Test of English as a Foreign Language (TOEFL).

The program helps applicants find suitable mentors. All prospective students, and their mentors, must guarantee that once they are accepted as students in the program, they will be able to devote essentially all of their time over a three-year period to training. For instance, a fellow in the Carver College of Medicine could spend no more than two months each year working on clinical assignments (e.g., two months of inpatient assignments or one month of inpatient assignments and one-half day per week in a clinic).

Financial Support

Funding of tuition and salaries or stipends is available from a number of sources. Contact the Translational Biomedicine Program for information.

Facilities

Training is conducted mainly in the laboratories and teaching facilities of the Carver College of Medicine and the College of Public Health. The University of Iowa Institute for Clinical and Translational Science Clinical Research Unit is available for research training. The program also is linked with the Carver College of Medicine's graduate training program in clinical research.

Associated Courses 

173:163 Seminar in Clinical and Translational Research 1 s.h.
050:225 Translational Biomedical Research arr.