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Translational Biomedicine Chair: Gary W. Hunnninghake (Internal Medicine) Executive committee: John Engelhardt (Anatomy and Cell Biology/Internal Medicine), William Haynes (Internal Medicine), Val Sheffield (Pediatrics), James Torner (Epidemiology) Affiliated faculty: Francois M. Abboud (Internal Medicine/Molecular Physiology and Biophysics), Nancy C. Andreasen (Psychiatry), Michael A. Apicella (Microbiology), Gale A. Bishop (Microbiology/Internal Medicine), Joseph A. Buckwalter (Orthopaedics and Rehabilitation), Garry R. Buettner (Free Radical and Radiation Biology), Trudy L. Burns (Biostatistics), Kevin P. Campbell (Molecular Physiology and Biophysics), Michael B. Cohen (Pathology), Beverley L. Davidson (Internal Medicine), Gerald F. Gebhart (Pharmacology), E. Peter Greenberg (Microbiology), Gregory S. Hageman (Ophthalmology and Visual Sciences), Donald D. Heistad (Internal Medicine/Pharmacology), Eric A. Hoffman (Radiology/Biomedical Engineering), Matthew A. Howard III (Neurosurgery), Ronald M. Lauer (Pediatrics), Steven R. Lentz (Internal Medicine), Andrew J. Lotery (Ophthalmology and Visual Sciences), Charles F. Lynch (Epidemiology), Allyn L. Mark (Internal Medicine), Paul B. McCray (Pediatrics), Geoffrey McLennan (Internal Medicine), Larry W. Oberley (Free Radical and Radiation Biology), M. Sue O'Dorisio (Pediatrics), Henry L. Paulson (Neurology), Stanley Perlman (Pediatrics/Microbiology), Timothy L. Ratliff (Urology), Andrew F. Russo (Molecular Physiology and Biophysics), D. Michael Shasby (Internal Medicine), Curt D. Sigmund (Internal Medicine/Molecular Physiology and Biophysics), Richard J.H. Smith (Otolaryngology), M. Bento Soares (Pediatrics/Biochemistry), Richard D. Sontheimer (Dermatology), Arthur A. Spector (Biochemistry/Internal Medicine), Jack T. Stapleton (Internal Medicine), John B. Stokes, III (Internal Medicine), Edwin M. Stone (Ophthalmology and Visual Sciences), William T. Talman (Neurology), James C. Torner (Epidemiology), Veronica Vieland (Biostatistics/Psychiatry), Robert B. Wallace (Epidemiology/Internal Medicine), George J. Weiner (Internal Medicine), Joel V. Weinstock (Internal Medicine), Jerrold P. Weiss (Internal Medicine), Michael J. Welsh (Internal Medicine/Molecular Physiology and Biophysics), Mary E. Wilson (Internal Medicine/Microbiology), Joseph Zabner (Internal Medicine) Graduate degrees: M.S., Ph.D. in Translational Biomedicine Web site: http://www.medicine.uiowa.edu/gptbr/ The Translational Biomedicine Program prepares skilled clinicians to pursue new knowledge about health and disease through patient-based research. The program's goal is to support the medical research enterprise in its efforts to advance the prevention, treatment, and cure of disease. Students in the program are trained to conduct rigorous, original clinical investigations using basic biological and physiological principles. They receive didactic training and engage in substantial mentored research opportunities in the areas of disease mechanisms, or etiology; new clinical insights into diagnosis or natural history of disease; objective assessment and outcome of therapeutic intervention; medical informatics; and development of new approaches to therapeutics. Graduate Programs The program offers a Master of Science and a Doctor of Philosophy in translational biomedicine. Master of Science The Graduate College requires a minimum of 30 s.h. of graduate credit for a Master of Science. However, Translational Biomedicine Program course work and research requirements over a three-year span are equivalent to 60 s.h. Each student's plan of study is based on his or her chosen discipline. All students take background courses in epidemiology, study design, and statistics as well as advanced courses in basic sciences relevant to their individual research areas. Students also must write a proposal for a K23 Mentored Patient-Oriented Research Career Development Award from the National Institutes of Health. For M.S. students, the K23 proposal replaces the thesis. A draft of the K23 proposal must pass an internal review by the end of the student's second year. Students may choose to pursue research areas in any of the health sciences disciplines, and they enjoy considerable flexibility in scheduling course work and beginning research. The following courses are required. All students must register for 050:224 and 050:225 each semester in the program.
| 050:224 Seminar in Translational Biomedicine |
1 s.h. |
| 050:225 Translational Biomedical Research |
arr. |
| 050:270 Responsible Conduct in Research |
0 s.h. |
| 060:204 Survival Skills for a Research Career |
1 s.h. |
| 171:161 Introduction to Biostatistics |
3 s.h. |
| 171:162 Design and Analysis of Biomedical Studies |
3 s.h. |
| 171:241 Applied Categorical Data Analysis |
3 s.h. |
| 173:140 Epidemiology I: Principles |
3 s.h. |
| 173:160 Introduction to Epidemiology Data Analysis with Computers |
2 s.h. |
| 173:240 Epidemiology II: Advanced Methods |
4 s.h. |
SAMPLE SCHEDULE First Semester
| 050:224 Seminar in Translational Biomedicine |
1 s.h. |
| 060:204 Survival Skills for a Research Career |
1 s.h. |
| 171:161 Introduction to Biostatistics |
3 s.h. |
| 173:140 Epidemiology I: Principles |
3 s.h. |
| 173:160 Introduction to Epidemiology Data Analysis with Computers |
2 s.h. |
Second Semester
| 050:224 Seminar in Translational Biomedicine |
1 s.h. |
| 050:225 Translational Biomedical Research |
arr. |
| 050:270 Responsible Conduct in Research |
0 s.h. |
| 171:162 Design and Analysis of Biomedical Studies |
3 s.h. |
| 171:241 Applied Categorical Data Analysis |
3 s.h. |
| 173:240 Epidemiology II: Advanced Methods |
4 s.h. |
Third and Following Semesters
| 050:224 Seminar in Translational Biomedicine |
1 s.h. |
| 050:225 Translational Biomedical Research |
arr. |
Doctor of Philosophy The Graduate College requires a minimum of 72 s.h. of graduate credit for a Doctor of Philosophy. For information about the Ph.D., contact the Translational Biomedicine Program. Admission The Translational Biomedicine Program welcomes students with diverse educational and scientific backgrounds and varied research interests. Applicants to the program should have strong interest and background in a health science profession and knowledge of basic sciences and medicine. They should hold an advanced degree in one of the health sciences (e.g., M.D., D.O., D.D.S., D.V.M., M.S.N., Pharm.D., Ph.D.). Applicants must meet the admission requirements of the Graduate College; see the Manual of Rules and Regulations of the Graduate College or the Graduate College section of the Catalog. Admission is based on applicants' undergraduate and graduate academic achievement, performance on the Graduate Record Examination (GRE) General Test, and letters of recommendation. Applicants whose first language is not English must take the Test of English as a Foreign Language (TOEFL). The program helps applicants find suitable mentors. All prospective students, and their mentors, must guarantee that once accepted to the program, applicants will be able to devote essentially all of their time over a three-year period to training. For instance, a fellow in the Carver College of Medicine could spend no more than two months each year working on clinical assignments (e.g., two months of inpatient assignments or one month of inpatient assignments and one-half day per week in a clinic). Financial Support Funding of tuition and salaries or stipends is available from a number of sources. Contact the Translational Biomedicine Program for information. Facilities Training is conducted mainly in the laboratories and teaching facilities of the Carver College of Medicine and the College of Public Health. The University of Iowa Clinical Research Center is available for research training. The program also is linked with the Carver College of Medicine's graduate training program in clinical research. Associated Courses
| 050:224 Seminar in Translational Biomedicine |
1 s.h. |
| 050:225 Translational Biomedical Research |
arr. |
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