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Carver College of Medicine
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Biochemistry Courses

099:001 Orientation and Introduction to the Field of Biochemistry   0 s.h.
Biochemistry and its application to other areas of basic sciences; biochemical studies, research, careers.
 
099:101 Technical Communication in Biochemistry   1 s.h.
Practical aspects of writing formal scientific papers and giving oral presentations on technical topics. Prerequisites: 099:120 or 099:130 or 099:140 or consent of instructor; and senior standing.
 
099:110 Biochemistry   3 s.h.
Basic concepts in modern biochemistry and molecular biology; understanding of life processes in molecular terms. Prerequisites: one year each of college-level biology and chemistry. Recommended: one semester of organic chemistry.
 
099:115 Undergraduate Independent Study   arr.
Experience in an active biochemistry research lab, learning and performing experiments relevant to the current projects in that lab; exploration of scientific literature on topic of interest; arranged in advance by student and faculty member. Prerequisite: first-year, sophomore, or junior standing.
 
099:120 Biochemistry and Molecular Biology I   3 s.h.
Physical and chemical foundations of biochemistry, structure of biological molecules, catalysis, transport, and oxidative reactions in biology; first course of two-semester sequence that concludes with 099:130. Prerequisites: two semesters of general chemistry and one of organic chemistry. Recommended: 002:010, 002:011, and an additional organic chemistry course.
 
099:130 Biochemistry and Molecular Biology II   3 s.h.
Metabolism of lipids and nitrogen-containing compounds; regulation and integration of metabolism; information transfer in procaryotes and eucaryotes; recombinant DNA techniques; chemistry and enzymology of replication, transcription, translation, cell transformation, and regulation of gene expression. Prerequisite: 099:120.
 
099:140 Experimental Biochemistry   4 s.h.
Use of modern instruments and techniques to fractionate, identify, and characterize constituents of biochemical systems. Prerequisites: 004:016 or 004:020, and 099:120.
 
099:155 Research, Independent Study   2-6 s.h.
Independent study and research in areas of interest to the student; arranged in advance by student and biochemistry honors advisor. Prerequisites: grade of B- or higher in 099:120, 099:130, and 099:140, and g.p.a. of B or higher in all three courses.
 
099:161 Biochemistry for Dental Students   4 s.h.
Biochemical concepts and application to clinical problems. Prerequisites: 004:121 or consent of instructor, and D.D.S. enrollment or consent of instructor. Recommended: 004:122.
 
099:162 Biochemistry for Pharmacy Students   4 s.h.
Biochemical concepts and application to clinical problems. Prerequisites: 004:121 and Pharm.D. enrollment, or consent of instructor. Recommended: 004:122.
 
099:163 Medical Biochemistry   4 s.h.
Biochemical concepts and application to clinical problems. Prerequisite: M.D. enrollment.
 
099:164 Biochemistry for Physician Assistant Students   3 s.h.
Aspects of general biochemistry necessary for understanding the biochemical basis of human disease; analysis of appropriate clinical cases. Prerequisite: 099:110 or equivalent biochemistry survey.
 
099:226 Enzyme Kinetics and Bioorganic Mechanisms   1-2 s.h.
Principles and applications of steady-state and transient enzyme kinetics; mechanisms of catalysis of biochemical reactions. Prerequisite: 099:120 or consent of instructor.
 
099:237 Topics in Molecular and Cell Biology   1-2 s.h.
Current topics in transcriptional regulation, chromatin structure and function, cell signaling pathways, regulation of development, molecular mechanisms of disease. Repeatable. Prerequisite: 156:201 or consent of instructor.
 
099:238 Topics in Biophysical Chemistry   1-2 s.h.
Current topics in structure and function of membranes or proteins; DNA-protein interactions; computational biochemistry; applications of NMR, X-ray diffraction, calorimetry, or spectroscopy. Repeatable. Prerequisite: 099:241 or 099:242 or consent of instructor.
 
099:241 Biophysical Chemistry I   3 s.h.
Experimental and theoretical techniques used to study structure and function of biological macromolecules; UV/Vis absorbance, circular dichroism, and fluorescence spectroscopies; X-ray crystallography of proteins, ultracentrifugation; application of thermodynamics to understand protein folding and protein-ligand binding. Prerequisites: one year of biochemistry and consent of instructor. Recommended: physical chemistry course.
 
099:242 Biophysical Chemistry II   3 s.h.
Enzyme kinetics and mechanisms, macromolecular interactions and dynamics, NMR spectroscopy.
 
099:261 Research Techniques   1-5 s.h.
Laboratory rotation for first-year graduate students in biochemistry.
 
099:275 Perspectives in Biocatalysis   1-3 s.h.
Applied enzymology, protein design, structure-activity relationships, biosensor technology, microbial transformations, biodegradation of environmental pollutants. Repeatable. Same as 004:275, 046:275, 052:275, 053:275, 061:275.
 
099:282 Seminar   0-1 s.h.
How to evaluate reports of scientific investigations critically; techniques for presenting scientific information.
 
099:283 Thesis Seminar   1 s.h.
Preparation and oral presentation of thesis proposal. Prerequisite: second-year graduate standing in biochemistry or consent of instructor.
 
099:292 Research Biochemistry   arr.
Thesis research.
 

 


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